Di‐tri‐octahedral smectite is a type of clay that adsorbs C. difficile toxins in vitro, 28 and is commonly used in the treatment of CDI in horses. Probiotic therapy has been evaluated in humans with CDI. Results have been somewhat conflicting and equivocal, however,
Smectite, a naturally occurring organomineral, has shown promise as a protectant against the overgrowth of pathogenic bacteria by reducing the harmful effects of bacterial toxins. Bio-Sponge™, the commercially available Di-Tri-Octahedral smectite product from Platinum Performance Inc.,
Di-tri-octahedral smectite for the prevention of post-operative diarrhea in equids with surgical disease of the large intestine: results of a randomized clinical trial. Vet J. 2009; 182(2):210-4 (ISSN: 1532-2971) Recommendations for Use. Healthy newborn foals: For best results, following an adequate intake of colostrum administer 30cc of Bio-Sponge™ Paste or 3 tablespoons (27.6g) of Bio-Sponge™ Powder mixed with 30cc of water 6 hours after the foal first nurses the mare. Article Unit Active component; Bio Sponge platinum: 9500 gr: Di-Tri-Octahedral Smectite: Equi-Sumo AP: 1000 ml: Ricebran oil, Herbs, Gamma-Orizanol: Quietex Paste Syringe Di-tri-octahedral smectite for the prevention of post-operative diarrhea in equids with surgical disease of the large intestine: Results of a randomized clinical trial more by Pablo Beldomenico Research performed in adult horses and foals, as well as through in vitro trials, indicates that Bio-Sponge® (Di-Tri Octahedral (DTO) smectite) is an effective tool Evaluation of in vitro properties of di-tri-octahedral smectite on clostridial toxins and growth. Equine Vet J 2003;35:638-641. 31. Lawler J, Hassel D, Traub- Dargatz Adsorptive effects of di-tri-octahedral smectite on. Clostridium perfringens alpha, beta, and beta-2 exotoxins and equine colostral antibodies.
Other Regulations: European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: Di-tri-octahedral smectite for the prevention of post-operative diarrhea in equids with surgical disease of the large intestine: Results of a randomized clinical trial more by Diana Hassel a Sharon Spier Charcoal or bentonite clay in powdered form (smectite clay; di-tri-octahedral smectite, known as Bio-Sponge) given via stomach tube can also absorb toxins. “It binds the toxins, Bio-Sponge™, the commercially available Di-Tri-Octahedral smectite product from Platinum Performance Inc., bound 99% of Clostridium difficile toxins A and B and Clostridium perfringens enterotoxins in one in vitro study and effectively neutralized Clostridium toxins in another study. Six horses were hospitalized, and lactated Ringer's solution and flunixin meglumine were administered IV. Additionally, 10% dextrose, corn syrup, and di-tri-octahedral smectite were administered PO. Twenty-seven horses died within 2 days after exposure. Two survivors (1 without clinical signs of toxicosis) made a complete recovery. Di-Tri-Octahedral Smectite for use in Post-Operative Diarrhea in Equids with Surgical Disease of the Large Intestine: Results of a randomized clinical trial.
METHODS: Substances commonly used in equine practice (activated charcoal composition, di-tri-octahedral smectite, mineral oil and activated charcoal) were tested for their binding capacity for HGA using an in vitro incubation method. Di‐tri‐octahedral smectite is a type of clay that adsorbs C. difficile toxins in vitro, 28 and is commonly used in the treatment of CDI in horses.
1 Nov 2017 Of these minerals, the smectite and the vermiculite group are defined by their The di / trioctahedral nature of the precipitates of this study were
Which drugs to choose — POLYSORB or smectite For many years in every human body accumulate many harmful substances. Poor diet, sedentary lifestyle, stress – all this contributes to the fact that over time, the body becomes clogged with unnecessary substances and overall health getting worse. For this reason, exacerbated many chronic diseases.
Di-Tri-Octahedral Smectite 97,500mg per scoop (97.5g)
"Di-tri-octahedral smectite was effective in neutralizing Clostridium difficile toxins A and B as well as Clostridium perfringens enterotoxin in vitro. However, di-tri-octahedral smectite did not inhibit the growth of Clostridium difficile and Clostridium perfringens, nor did it interfere with the activity of metronidazole." See: Di-tri-octahedral smectite (BiospongeTM) may help absorb luminal intestinal toxins. Nutritional support . Total or partial parenteral (TPN, PPN) nutrition should be considered in neonates. Adsorptive effects of di-tri-octahedral smectite on Clostridium perfringens alpha, beta, and beta-2 exotoxins and equine colostral antibodies.
Smectite.
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In vivo s … The aim of this study was to evaluate the effects of a commercially available di-tri-octahedral (DTO) smectite product on clinical signs and prevalence of post-operative diarrhea in horses with colic associated with disease of the large intestine.
Di-tri-octahedral smectite for the prevention of post-operative diarrhea in equids with surgical disease of the large intestine: results of a randomized clinical trial Hassel, D.M., Smith, P.A., Nieto, J.E., Beldomenico, P. and Spier, S.J. (2009) Vet. J. 182, 210-214.
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2011-01-10 · Smectite clay doesn’t recognize these different substances, it only recognizes the positive electrical charge. It is also very alkaline with a pH of 7.4. As clay moves through the GI tract and colon, it picks up the positively charged substances, and leaves the body through the alimentary canal taking the toxins with it.
3 0. Weese J, Cote N, deGannes R. Evaluation of in vitro properties of di-tri-octahedral smectite on clostridial toxins and growth. Equine Vet J 2003;35:638-641.
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Preliminary studies using a model of lincomycin-induced colitis suggested that di-tri-octahedral (DTO) smectite, a natural clay material, may be useful for the treatment and prevention of colitis in horses (Herthel, 2000).
Description Chemical name. Di-tri-octahedral smectite. Physical properties. A natural, hydrated aluminomagnesium silicate "clay". Storage requirements.